The Translational Microbiome Research Forum is an online resource for scientists engaged in translational microbiome research to access current, topical information and to provide a platform to exchange knowledge and ideas. We encourage you to participate by actively using the commenting system, by submitting links, resources, and your original research, and by joining our email list to receive updates when new content is posted.

  • Microbes in pressed grapes may predict flavor metabolites in the finished wine

    Washington, DC – June 9, 2016 -The microbial mix found in grape juice during the winemaking process may help shape the terroir of a finished wine, report food scientists at the University of California, Davis.

  • uBiome Doubles Research Grant to Award Two Microbiome Researchers up to $100,000 Each

    uBiome, the leading microbial genomics company, will double the number of academic researchers it will support after two projects tied for first place in a public vote to decide between six short-listed finalists.

  • Acetate’s unexpected role in obesity
    Gut Microbiome Rodent

    Gut microbiome in rodents makes the small molecule, which promotes fat storage and increased appetite, study shows Eating a high-fat diet certainly puts people at risk for obesity, but diet is not the only driver of corpulence. In recent years, scientists have also shown that the gut microbiome is also a culprit in weight gain.

  • Jason Tetro aims to rehabilitate microbes’ bad reputation with The Germ Files

    Halfway through my conversation with Jason Tetro, an expert in health-related microbiology, I wonder: if most germs are as innocuous as he explains them to be in his new book, The Germ Files, why are we all carrying around tiny squeeze bottles of hand sanitizer?

  • Scientists Gather to Discuss Novel Connections Between Gut Microbiome and Brain Disorders

    Increasing evidence suggests that our gut microbiome is able to regulate brain processes and trigger neurological disorders, such as multiple sclerosis (MS). Scientists from around the world discussed these themes at the recent Congress of the European Academy of Neurology in Copenhagen, Denmark.

  • The man who can map the chemicals all over your body

    Pieter Dorrestein uses mass spectrometry to eavesdrop on the molecular conversations between microbes and their world.

  • Unlocking the Mysteries of the Microbiome

    In the early 2000s, JCVI researchers pioneered in the exploration of the human microbiome, the community of microbes that live in and on the human body.

  • Connections between gut microbiota and the brain

    Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the “gut-brain axis” for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract.

  • Inner Workings: Ancient teeth reveal clues about microbiome evolution

    Christina Warinner often spends the better part of her day rubbing toothbrushes and dental scrapers against filthy jaws. But she is not a dental hygienist. A molecular anthropologist at the University of Oklahoma, Warinner chips away at ancient teeth to collect dental calculus, the thick chalky layer that hygienists scour away. Read more at: PNAS

  • FAQ on Microbiology of Built Environments from the American Academy of Microbiology

    There is a report out from the American Academy of Microbiology that is based on the “Microbiology of the Built Environment” colloquium they hosted in September 2015.

  • The Hidden World of Microbiomes

    What are microbiomes and how many do you have in your body? Read the comic or watch the video here: PHD Comics.

  • Micro Size, Macro Opportunity: Looking for New Applications of our Microbiome

    The “microbiome” is a bustling city of diverse and dynamic bacteria, and its potential for helping patients has scientists and researchers excited for the future.

  • Working with Germ-Free Mice

    The volume of published studies employing axenic or germ-free mice increased dramatically over the past 15 years, in part due to growing interest in microbiome research.

  • Episode 05: Micro But Mighty

    Let’s start with a definition: what is the microbiome? Simply put, the microbiome is the collection of microbes (mostly bacteria) that live in and on your body.

  • How to Culture Uncultured Organisms

    Many microorganisms are “unculturable,” or at least not able to grow in known media. Now, a new tool enables researchers to predict what nutrients organisms need to thrive in the lab, eliminating most of the guesswork involved in setting up new cultures.

  • The Mycobiome

    At a workshop held at the National Institutes of Health  (NIH) last September on the role of human microbiota in infectious disease, I was disheartened not to hear a single talk on the fungal community—the mycobiome.

  • How the Immune System Impacts Gut Microbiota Evolution

    In a novel study demonstrating the influence of the immune system on gut bacteria evolution, scientists from the Insitito Gulbenkian de Ciencia (IGC) in Portugal have made a solid case for the use of personalized medicine for immunocompromised patients with intestinal problems.

  • Project Director, Product Innovation & Development
    Taconic Logo

    This is a key role in the Portfolio Innovation and Development area and is responsible for promoting and developing the Microbiome Portfolio initiative. The Project Leader will drive the commercialization of the portfolio.

  • Microbiome & Mice 2016: Advancing Microbiome Research Symposium

    Watch the videos from the recent scientific symposium “Microbiome & Mice 2016: Advancing Microbiome Research”.

  • Events
    We maintain a calendar of events and meetings related to the field of Microbiome Research. Check it often for new events and conferences, or submit something for the calendar here.

  • The composition of the microbiota modulates allograft rejection

    Abstract Transplantation is the only cure for end-stage organ failure, but without immunosuppression, T cells rapidly reject allografts. While genetic disparities between donor and recipient are major determinants of the kinetics of transplant rejection, little is known about the contribution of environmental factors.

  • Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection

    Abstract Background. The elderly host is highly susceptible to severe disease and treatment failure in Clostridium difficile infection (CDI). We investigated how treatment with vancomycin in the aged host influences systemic and intestinal humoral responses and select intestinal microbiota.

  • Advancing microbial sciences by individual-based modelling

    Abstract Remarkable technological advances have revealed ever more properties and behaviours of individual microorganisms, but the novel data generated by these techniques have not yet been fully exploited.

  • Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

    Abstract Highlights Maternal high-fat diet (MHFD) induces behavioral alterations in offspring MHFD causes alterations in gut microbial ecology in offspring

  • RNA-stable isotope probing: from carbon flow within key microbiota to targeted transcriptomes
    RNA-based stable isotope probing

    Abstract Highlights RNA-SIP allows for a labelling-based detection of process-relevant microbes independent of cellular replication or growth. Recent RNA-SIP based advances in our understanding of carbon flow in complex natural microbiota, of organismic interactions and in environmental biotechnology are summarized. The combination of RNA-SIP and next-generation sequencing is a promising strategy for targeted environmental transcriptomics.

  • The structural alteration of gut microbiota in low-birth-weight mice undergoing accelerated postnatal growth

    Abstract The transient disruption of gut microbiota in infancy by antibiotics causes adult adiposity in mice. Accelerated postnatal growth (A) leads to a higher risk of adult metabolic syndrome in low birth-weight (LB) humans than in normal birth-weight (NB) individuals, but the underlying mechanism remains unclear.

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