The Translational Microbiome Research Forum is an online resource for scientists engaged in translational microbiome research to access current, topical information and to provide a platform to exchange knowledge and ideas. We encourage you to participate by actively using the commenting system, by submitting links, resources, and your original research, and by joining our email list to receive updates when new content is posted.

  • From mice, clues to microbiome’s influence on metabolic disease
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    The community of microorganisms that resides in the gut, known as the microbiome, has been shown to work in tandem with the genes of a host organism to regulate insulin secretion, a key variable in the onset of the metabolic disease diabetes. That is the primary finding of a study published Feb. 14 in the […]

  • Melatonin prevents obesity through modulation of gut microbiota in mice
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    Abstract Excess weight and obesity are severe public health threats worldwide.

  • Feeling stressed? Try prebiotics
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    Stress could upset the gut’s microbiome, as well as restful sleep — essential elements for a healthy life.

  • High-Fiber Diet Keeps Intestinal Walls Intact
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    A low-fiber diet causes fiber-eating microbes to dwindle, opening up real estate for mucus munchers that make the intestine more vulnerable to infection. Christopher Intagliata reports.

  • The Secret Lives of Marine Mammal Microbes
    Indo-Pacific bottlenose dolphin. Credit: Aude Steiner Wikimedia (CC BY-SA 1.0)


    Probing the mystery of what goes on inside the guts of dolphins and whales…

  • ADA funds Kostic Lab to create model linking the microbiome to type 1 diabetes
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    The American Diabetes Association (ADA) has awarded Joslin Diabetes Center assistant investigator Aleksandar Kostic, Ph.D., a $1.625-million grant under its Pathway to Stop Diabetes program, which seeks to bring new investigators and new perspectives to diabetes research.

  • USDA Funds Study of Plant and Animal Phenomics and Microbiomes
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    The USDA’s National Institute of Food and Agriculture (NIFA) this week announced 11 grants totaling $3 million for Early Concept Grants for Exploratory Research (EAGER) projects focused on plant and animal phenomics and microbiomes.

  • Cruciferous vegetables help the immune system to fight intestinal pathogens
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    A study in mice shows that eating cruciferous vegetables—including broccoli, kale and cauliflower – helps the immune system to fight intestinal pathogens. The research might have implications for people with inflammatory bowel diseases.

  • UChicago startups focus on microbiome medicine
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    Two startup companies founded by UChicago faculty are leveraging the microbiome to develop new medications that could prevent food allergies, stop infections, and treat disease. ClostraBio, started by Cathryn Nagler, PhD,

  • Home-Made Cost Effective Preservation Buffer Is a Better Alternative to Commercial Preservation Methods for Microbiome Research
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    The investigation of wildlife gastrointestinal microbiomes by next-generation sequencing approaches is a growing field in microbial ecology and conservation.

  • Free Webinar: Precision Medicine – Learning Lessons From the Microbiome
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    Summary The influence of gut microbiota on human health has been well documented, particularly in the case of metabolic disorders, such as type 1 and type 2 diabetes.

  • VIDEO: Native squid and its bacterium may help human and environmental health
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    The humble Hawaiian bobtail squid is helping to build the University of Hawaiʻi’s capacity in the hot field of microbiome research.

  • VIDEO: Precision Medicine: Learning Lessons From the Microbiome
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    Summary The influence of gut microbiota on human health has been well documented, particularly in the case of metabolic disorders, such as type 1 and type 2 diabetes.

  • ILAR Roundtable workshop on Animal Models for Microbiome Research
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    Video recordings and presentations from the ILAR Roundtable workshop on Animal Models for Microbiome Research held on December 19-20, 2016: See more at: ILAR Roundtable

  • Diet, the Gut Microbiome, and Autism/Cell, June 16, 2016 (Vol. 165, Issue 7)
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    Are autism-related social behaviors in offspring related to mom’s diet? Mauro Costa-Mattioli and his colleagues of Baylor College of Medicine explain a potential link through the gut microbiome in this video.

  • Rob Knight – The Current Toolkit for Studying Microbiome/Built Environment Interfaces
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    Rob Knight, University of California San Diego, presents on the wide variety of tools and applications available to study and quantify microbiome/built environment interfaces and interactions.

  • Microbiome: Gut Bugs and You | Warren Peters | TEDxLaSierraUniversity
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    Can gut bugs change the world? Join Warren Peters on a journey into understanding your microbiome and the new discoveries changing the way we understand diabetes, obesity, Alzheimer’s disease, autism, and our everyday health and wellness. Watch more at: YouTube

  • Expert Panel Discussions to be Highlight of Agenda at the 3rd Annual Translational Microbiome Conference
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    Minneapolis, MN – February 15, 2017 – Arrowhead Publishers is pleased to announce that a variety of expert panel discussions have been announced for its upcoming 3rd Annual Translational Microbiome Conference.

  • How the Microbiome Can Affect Cancer
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    Post by William G. Nelson, MD, PhD, Editor-in-Chief, Cancer Today: Over the past few years, scientists have come to a deeper understanding of how microorganisms can cause chronic human diseases, based on the recognition that each human body contains at least 40 trillion microorganisms.

  • Events
    We maintain a calendar of events and meetings related to the field of Microbiome Research. Check it often for new events and conferences, or submit something for the calendar here.

  • Host Genotype and Gut Microbiome Modulate Insulin Secretion and Diet-Induced Metabolic Phenotypes
    F2 Weight Glucose Insulin liver TG and AUC for CC founder mice


    Highlights •Host genotype affects the abundance of taxa associated with metabolic disease •Gut microbiota affects susceptibility to diet-induced metabolic disease •The gut microbiome modulates insulin secretion

  • Host Genotype and Gut Microbiome Modulate Insulin Secretion and Diet-Induced Metabolic Phenotypes
    Keller 58


    Highlights •Host genotype affects the abundance of taxa associated with metabolic disease •Gut microbiota affects susceptibility to diet-induced metabolic disease •The gut microbiome modulates insulin secretion

  • A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
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    Highlights •Characterized synthetic bacterial communities enable functional insights in vivo •Low-fiber diet promotes expansion and activity of colonic mucus-degrading bacteria •Purified prebiotic fibers do not alleviate degradation of the mucus layer •Fiber-deprived gut microbiota promotes aggressive colitis by an enteric pathogen

  • Human and rat gut microbiome composition is maintained following sleep restriction

    Abstract Insufficient sleep increasingly characterizes modern society, contributing to a host of serious medical problems.

  • Microbiota composition of simultaneously colonized mice housed under either a gnotobiotic isolator or individually ventilated cage regime
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    Abstract Germ-free rodents colonized with microbiotas of interest are used for host-microbiota investigations and for testing microbiota-targeted therapeutic candidates.

  • Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota
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    Abstract Alzheimer’s disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder.

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