Inside the human body lives a complex community of microorganisms, bacteria, viruses and fungi known as the microbiome. Found primarily in the intestine, the microbiome plays an integral role in human health and wellness.
Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28 in the journal Nature Microbiology.
Mouse study finds potential link between microbiome and anxiety, learning difficulty
CALTECH/S. MAZMANIAN LAB Many people with Parkinson’s disease have digestive symptoms like constipation years before they have neurological symptoms, and scientists have found differences in the gut microbiome compositions of patients with Parkinson’s disease and healthy controls.
A new study shows how a bacterium that is often abundant on human skin secretes an enzyme with antioxidant properties that not only helps the microorganism itself survive, but it may also protect us against damage and disease.
Age-related Macular Degeneration (AMD) is the leading cause of irreversible blindness in the industrialized world, affecting over 10 million individuals in North America.
Researchers at Oregon State University and other institutions have discovered an important link between the immune system, gut bacteria and glucose metabolism — a “cross-talk” and interaction that can lead to type 2 diabetes and metabolic syndrome when not functioning correctly.
A new study shows that a strain of bacteria was able to kill pneumonia inside the lungs of sick rats.
Each of us has a community of microbes that lives in our digestive system. Scientists call this community our gut microbiome. It plays many important roles in our bodies, like helping to digest food, regulating our immune system, preventing diseases, and even affecting our appetites and our emotions.
pgEd’s newest quiz, “You Are Not Alone: The Microbiome” is live and ready for people to make their way through the questions, learn about the bacteria that are an essential part of our bodies
What’s next for microbiome research? In the third and final episode on the microbiome, we are joined by Dr. Camille Konopnicki, a post-doctoral fellow in the lab of Dr. Andrew Goodman
What has the microbiome taught us? In the second episode on the microbiome, we are joined by Yale rheumatologist and assistant professor of Immunobiology and Medicine, Dr. Martin Kriegel to discuss articles published in our issue
Want to learn more about the microbiome? In the first episode of three on the microbiome, the focus topic for the September 2016 issue of the Yale Journal of Biology and Medicine, we will be discussing the history of the field, current techniques used in microbiome research, and how the microbiome influences our health.
NEW ORLEANS — In this video exclusive, C. Ronald Kahn, MD, chief academic officer and senior investigator at Joslin Diabetes Center and the Mary K. Iacocca professor of medicine at Harvard Medical School, discusses the role of the gut microbiome in relation to genes and environment in determining body composition and metabolic health.
Gut Check is a scientific, strategic and competitive board game designed to be enjoyable for scientists, students and game enthusiasts alike. The game consists of several card types, including beneficial, opportunistic and pathogenic microbes, infections and events.
Bacteria have co-evolved with us for thousands of years. We now understand that they are closely linked to many aspects of health. But, in most cases, the complex influences of microbiota on our health is not yet functionally understood.
There is a report out from the American Academy of Microbiology that is based on the “Microbiology of the Built Environment” colloquium they hosted in September 2015.
Insight from Megan M. MacBride, PhD: Malaria is a serious global health hazard, with 214 million new cases worldwide in 2015 according to the World Health Organization.
Arrowhead Publishers has announced the preliminary speaking faculty for the 3rd Annual Translational Microbiome Conference. This conference, taking place April 11-13, 2017 in Boston, MA,
Significance New interventions are needed to improve bone health and reduce the risk for osteoporosis and fracture. Dysbiosis is increasingly linked to metabolic abnormalities, although the effect of the microbiota on skeletal health is poorly understood.
Highlights •Gut microbiota alter host histone acetylation and methylation in multiple tissues •Western diet suppresses microbiota-driven SCFA production and chromatin effects •SCFAs recapitulate microbiota-driven chromatin and transcriptional effects
Highlights •Pathogenic TH17 cells migrate from the gut to the kidney in autoimmunity •TH17 cells egress the intestine in a S1PR1-dependent manner in glomerulonephritis •Targeting microbiota-induced TH17 cells ameliorates extraintestinal TH17 responses
Abstract In tackling the obesity pandemic, significant efforts are devoted to the development of effective weight reduction strategies, yet many dieting individuals fail to maintain a long-term weight reduction, and instead undergo excessive weight regain cycles.
Highlights •Gut microbes promote α-synuclein-mediated motor deficits and brain pathology •Depletion of gut bacteria reduces microglia activation •SCFAs modulate microglia and enhance PD pathophysiology •Human gut microbiota from PD patients induce enhanced motor dysfunction in mice
Abstract Previously, we demonstrated that Lactobacillus salivarius was more abundant in patients with rheumatoid arthritis (RA), an inflammatory autoimmune disease wherein the gut microbiota is altered, than in healthy individuals. However, the effect of L. salivarius in RA is unclear.