The Translational Microbiome Research Forum is an online resource for scientists engaged in translational microbiome research to access current, topical information and to provide a platform to exchange knowledge and ideas. We encourage you to participate by actively using the commenting system, by submitting links, resources, and your original research, and by joining our email list to receive updates when new content is posted.

  • Are You Your Microbiome? Ed Yong Explains It All

    Writer Ed Yong has been chronicling the science of microbial life for years at such outlets as The New York Times, the Atlantic (where he is now a staff writer) and his blog, Not Exactly Rocket Science (currently hosted by National Geographic).

  • Mouse microbes may make scientific studies harder to replicate

    In the first experiment, Laura McCabe’s lab seemed to hit a home run. The physiologist and her team at Michigan State University (MSU) in East Lansing were testing how a certain drug affects bone density, and they found that treated lab mice lost bone compared with controls.

  • First public collection of bacteria from the intestine of mice

    Mouse models are extensively used in pharmaceutical and medical research, and the microbes in their intestine can have an impact on research. However, there is still insufficient information available about many bacteria in mice.

  • Understanding diverse microbial communities: An interview with A. Murat Eren (Meren)

    It’s clear that microbes play a crucial role in practically every aspect of ecosystems globally. From the deepest, most remote and unexplored regions of the ocean, to the human oral cavity, there are diverse microbial assemblages driving Earth’s biogeochemical cycles.

  • NASA releases ‘Microbiomics: The Living World In and On You’

    NASA’s Human Research Program (HRP) is releasing a video titled “Microbiomics: The Living World In and On You” to highlight microbial research on the International Space Station.

  • How Miraculous Microbes Help Us Evolve Better, Faster, Stronger

    Invisible yet crucial, our microbial partners add a gene-swapping plot twist to evolutionary theory.

  • Antibiotics weaken Alzheimer’s disease progression through changes in the gut microbiome

    Long-term antibiotic treatment in mice decreases levels of disease-causing plaques and enhances neuroinflammatory activity of microglial cells.

  • New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

    Studies have shown that bariatric surgery can lead to remission of type 2 diabetes mellitus (T2DM) in rodents and humans, but this beneficial effect cannot be explained solely by weight loss.

  • Gut bacteria can cause, predict and prevent rheumatoid arthritis

    The bacteria in your gut do more than break down your food.

  • Metabolomics – A Key Technology for Microbiome Research
    Metabolic Process Microbiome

    Bacteria have co-evolved with us for thousands of years. We now understand that they are closely linked to many aspects of health. But, in most cases, the complex influences of microbiota on our health is not yet functionally understood.

  • FAQ on Microbiology of Built Environments from the American Academy of Microbiology

    There is a report out from the American Academy of Microbiology that is based on the “Microbiology of the Built Environment” colloquium they hosted in September 2015.

  • The Hidden World of Microbiomes

    What are microbiomes and how many do you have in your body? Read the comic or watch the video here: PHD Comics.

  • Micro Size, Macro Opportunity: Looking for New Applications of our Microbiome

    The “microbiome” is a bustling city of diverse and dynamic bacteria, and its potential for helping patients has scientists and researchers excited for the future.

  • Working with Germ-Free Mice

    The volume of published studies employing axenic or germ-free mice increased dramatically over the past 15 years, in part due to growing interest in microbiome research.

  • Episode 05: Micro But Mighty

    Let’s start with a definition: what is the microbiome? Simply put, the microbiome is the collection of microbes (mostly bacteria) that live in and on your body.

  • How to Culture Uncultured Organisms

    Many microorganisms are “unculturable,” or at least not able to grow in known media. Now, a new tool enables researchers to predict what nutrients organisms need to thrive in the lab, eliminating most of the guesswork involved in setting up new cultures.

  • The Mycobiome

    At a workshop held at the National Institutes of Health  (NIH) last September on the role of human microbiota in infectious disease, I was disheartened not to hear a single talk on the fungal community—the mycobiome.

  • WEBINAR: Intro to the Microbiome

    Interest in the microbiome and its role in health and disease is a rapidly growing research focus for academic institutions, biotech and pharmaceutical companies.

  • WEBINAR: Exercise as a Lens to View the Microbiome and Intestinal Health

    Join us for a webinar on August 4, 2016 exploring the complex relationship between diet, exercise and the microbiome.

  • Events
    We maintain a calendar of events and meetings related to the field of Microbiome Research. Check it often for new events and conferences, or submit something for the calendar here.

  • The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota

    Abstract Intestinal bacteria influence mammalian physiology, but many types of bacteria are still uncharacterized. Moreover, reference strains of mouse gut bacteria are not easily available, although mouse models are extensively used in medical research.

  • The effect of DNA extraction methodology on gut microbiota research applications

    Abstract Background The effect that traditional and modern DNA extraction methods have on applications to study the role of gut microbiota in health and disease is a topic of current interest.

  • A new way to contemplate Darwin’s tangled bank: how DNA barcodes are reconnecting biodiversity science and biomonitoring

    Abstract Encompassing the breadth of biodiversity in biomonitoring programmes has been frustrated by an inability to simultaneously identify large numbers of species accurately and in a timely fashion.

  • Gut Microbial Membership Modulates CD4 T Cell Reconstitution and Function after Sepsis

    Abstract Transient lymphopenia is one hallmark of sepsis, and emergent data indicate the CD4 T cell compartment in sepsis survivors is numerically and functionally altered (when examined at the Ag-specific level) compared with nonseptic control subjects.

  • Fast comparison of genomic and meta-genomic reads with alignment-free measures based on quality values

    Abstract Background Sequencing technologies are generating enormous amounts of read data, however assembly of genomes and metagenomes remain among the most challenging tasks.

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