Researchers from The Ohio State University have discovered that spinal cord injury alters the type of bacteria living in the gut and that these changes can exacerbate the extent of neurological damage and impair recovery of function.
The community of bacteria that live in our intestines, also called the “gut microbiome,” is important to normal intestinal function.
As discussed in Part 1 of this article, it is now clear that the gut microbiome participates in many human physiologic functions and is considered a target for therapeutic intervention. Part 2 of this article will briefly address some of the fundamental scientific questions that underpin such drug development.
In the 17th century, the “Father of Microbiology,” Anton van Leeuwenhoek, used his newly invented microscope to describe “animalcules” in the plaque from his own teeth.
What kick-starts the aggregation of pathological proteins in neurodegenerative disease? In the October 6 Scientific Reports, researchers led by Robert Friedland at the University of Louisville School of Medicine, Kentucky, present more evidence that microorganisms might play a role.
Could neurodegenerative diseases such as Alzheimer’s and Parkinson’s originate in the gut? New research from the U.S., published in the journal Nature, shows that certain proteins produced by gut bacteria may be linked to neurodegeneration in rats.
In the mouse gut, infectious diarrhea caused by microbes promotes growth of a certain type of Escherichia coli bacteria and worsens disease severity, according to a new study in PLOS Pathogens.
Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has been honored with the Steven C. Beering Award for his seminal contributions to establishing the field of human microbiome research.
A hot tip for this year’s Nobel Prize in physiology or medicine was Jeffrey Gordon. (In case you missed it, the prize went to Yoshinori Ohsumi.)
Gut Check is a scientific, strategic and competitive board game designed to be enjoyable for scientists, students and game enthusiasts alike. The game consists of several card types, including beneficial, opportunistic and pathogenic microbes, infections and events.
Bacteria have co-evolved with us for thousands of years. We now understand that they are closely linked to many aspects of health. But, in most cases, the complex influences of microbiota on our health is not yet functionally understood.
There is a report out from the American Academy of Microbiology that is based on the “Microbiology of the Built Environment” colloquium they hosted in September 2015.
What are microbiomes and how many do you have in your body? Read the comic or watch the video here: PHD Comics.
The “microbiome” is a bustling city of diverse and dynamic bacteria, and its potential for helping patients has scientists and researchers excited for the future.
The volume of published studies employing axenic or germ-free mice increased dramatically over the past 15 years, in part due to growing interest in microbiome research.
Let’s start with a definition: what is the microbiome? Simply put, the microbiome is the collection of microbes (mostly bacteria) that live in and on your body.
Many microorganisms are “unculturable,” or at least not able to grow in known media. Now, a new tool enables researchers to predict what nutrients organisms need to thrive in the lab, eliminating most of the guesswork involved in setting up new cultures.
November 3, 2016 | Bolger Center in Potomac, MD November 17, 2016 | Conference Chicago at University Center in Chicago, IL This complimentary symposium will bring together hundreds of academic and biopharmaceutical industry scientists and executives to discuss microbiome science and its translational applications.
Call for presenters and posters at Taconic’s Advancing Microbiome Research Symposium: Microbiome & Disease. Event is November 17th in Chicago, IL. Submission deadline is September 19th. Get more details here: Register Now!
Abstract Addiction to cocaine and other psychostimulants represents a major public health crisis. The development and persistence of addictive behaviors comes from a complex interaction of genes and environment – the precise mechanisms of which remain elusive.
Abstract The trillions of microbes that exist in the gastrointestinal tract have emerged as pivotal regulators of mammalian development and physiology.
Abstract The gut microbiota modulates obesity and associated metabolic phenotypes in part through intestinal farnesoid X receptor (FXR) signaling.
Abstract Rotavirus is the leading cause of severe acute gastroenteritis among children worldwide. Despite effective vaccines, inexpensive alternatives such as probiotics are needed. The aim of this study was to assess the ability of probiotic candidate Bifidobacterium thermophilum RBL67 to inhibit rotavirus infection.
Abstract Numerous studies have shown the efficacy of phage therapy in reducing foodborne pathogen carriage in food animals. Fewer studies have focused on host reactions, especially in terms of phage-mediated acute immune responses and effects on the gut microbiome.
Abstract Chronic sleep fragmentation (SF) commonly occurs in human populations, and although it does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors ultimately promoting obesity and insulin resistance.