The Translational Microbiome Research Forum is an online resource for scientists engaged in translational microbiome research to access current, topical information and to provide a platform to exchange knowledge and ideas. We encourage you to participate by actively using the commenting system, by submitting links, resources, and your original research, and by joining our email list to receive updates when new content is posted.

  • Gut bacteria can aid recovery from spinal cord injury, study suggests

    Researchers from The Ohio State University have discovered that spinal cord injury alters the type of bacteria living in the gut and that these changes can exacerbate the extent of neurological damage and impair recovery of function.

  • Researchers show how spinal cord injury causes profound changes in gut microbiota

    The community of bacteria that live in our intestines, also called the “gut microbiome,” is important to normal intestinal function.

  • Tapping the Human Gut Microbiome, Part 2
    What's going on in there?

    As discussed in Part 1 of this article, it is now clear that the gut microbiome participates in many human physiologic functions and is considered a target for therapeutic intervention. Part 2 of this article will briefly address some of the fundamental scientific questions that underpin such drug development.

  • Tapping the Human Gut Microbiome, Part 1 The Next Frontier for Novel Therapeutics
    Who's in charge here?

    In the 17th century, the “Father of Microbiology,” Anton van Leeuwenhoek, used his newly invented microscope to describe “animalcules” in the plaque from his own teeth.

  • Could Bacterial Amyloid Trigger Parkinson’s Pathology?

    What kick-starts the aggregation of pathological proteins in neurodegenerative disease? In the October 6 Scientific Reports, researchers led by Robert Friedland at the University of Louisville School of Medicine, Kentucky, present more evidence that microorganisms might play a role.

  • Gut microbiota may have role in neurodegenerative diseases: study

    Could neurodegenerative diseases such as Alzheimer’s and Parkinson’s originate in the gut? New research from the U.S., published in the journal Nature, shows that certain proteins produced by gut bacteria may be linked to neurodegeneration in rats.

  • Diarrhea-Causing Bacteria Promote Growth of Crohn’s-Linked Microbe in Mice

    In the mouse gut, infectious diarrhea caused by microbes promotes growth of a certain type of Escherichia coli bacteria and worsens disease severity, according to a new study in PLOS Pathogens.

  • Gordon receives Beering Award

    Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has been honored with the Steven C. Beering Award for his seminal contributions to establishing the field of human microbiome research.

  • If there was a Nobel silver medal, I’d award it to Jeffrey Gordon and our gut microbes

    A hot tip for this year’s Nobel Prize in physiology or medicine was Jeffrey Gordon. (In case you missed it, the prize went to Yoshinori Ohsumi.)


    Gut Check is a scientific, strategic and competitive board game designed to be enjoyable for scientists, students and game enthusiasts alike. The game consists of several card types, including beneficial, opportunistic and pathogenic microbes, infections and events.

  • Metabolomics – A Key Technology for Microbiome Research
    Metabolic Process Microbiome

    Bacteria have co-evolved with us for thousands of years. We now understand that they are closely linked to many aspects of health. But, in most cases, the complex influences of microbiota on our health is not yet functionally understood.

  • FAQ on Microbiology of Built Environments from the American Academy of Microbiology

    There is a report out from the American Academy of Microbiology that is based on the “Microbiology of the Built Environment” colloquium they hosted in September 2015.

  • The Hidden World of Microbiomes

    What are microbiomes and how many do you have in your body? Read the comic or watch the video here: PHD Comics.

  • Micro Size, Macro Opportunity: Looking for New Applications of our Microbiome

    The “microbiome” is a bustling city of diverse and dynamic bacteria, and its potential for helping patients has scientists and researchers excited for the future.

  • Working with Germ-Free Mice

    The volume of published studies employing axenic or germ-free mice increased dramatically over the past 15 years, in part due to growing interest in microbiome research.

  • Episode 05: Micro But Mighty

    Let’s start with a definition: what is the microbiome? Simply put, the microbiome is the collection of microbes (mostly bacteria) that live in and on your body.

  • How to Culture Uncultured Organisms

    Many microorganisms are “unculturable,” or at least not able to grow in known media. Now, a new tool enables researchers to predict what nutrients organisms need to thrive in the lab, eliminating most of the guesswork involved in setting up new cultures.

  • The Mycobiome

    At a workshop held at the National Institutes of Health  (NIH) last September on the role of human microbiota in infectious disease, I was disheartened not to hear a single talk on the fungal community—the mycobiome.

  • Advancing Microbiome Research Symposium: Microbiome & Disease

    November 3, 2016 | Bolger Center in Potomac, MD November 17, 2016 | Conference Chicago at University Center in Chicago, IL This complimentary symposium will bring together hundreds of academic and biopharmaceutical industry scientists and executives to discuss microbiome science and its translational applications.

  • Advancing Microbiome Research Symposium: Microbiome & Disease

    Call for presenters and posters at Taconic’s Advancing Microbiome Research Symposium: Microbiome & Disease. Event is November 17th in Chicago, IL. Submission deadline is September 19th. Get more details here: Register Now!

  • Events
    We maintain a calendar of events and meetings related to the field of Microbiome Research. Check it often for new events and conferences, or submit something for the calendar here.

  • Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine

    Abstract Addiction to cocaine and other psychostimulants represents a major public health crisis. The development and persistence of addictive behaviors comes from a complex interaction of genes and environment – the precise mechanisms of which remain elusive.

  • Gut dysbiosis impairs recovery after spinal cord injury

    Abstract The trillions of microbes that exist in the gastrointestinal tract have emerged as pivotal regulators of mammalian development and physiology.

  • Farnesoid X Receptor Signaling Shapes the Gut Microbiota and Controls Hepatic Lipid Metabolism

    Abstract The gut microbiota modulates obesity and associated metabolic phenotypes in part through intestinal farnesoid X receptor (FXR) signaling.

  • Study of the Ability of Bifidobacteria of Human Origin to Prevent and Treat Rotavirus Infection Using Colonic Cell and Mouse Models

    Abstract Rotavirus is the leading cause of severe acute gastroenteritis among children worldwide. Despite effective vaccines, inexpensive alternatives such as probiotics are needed. The aim of this study was to assess the ability of probiotic candidate Bifidobacterium thermophilum RBL67 to inhibit rotavirus infection.

  • The impact of orally administered phages on host immune response and surrounding microbial communities

    Abstract Numerous studies have shown the efficacy of phage therapy in reducing foodborne pathogen carriage in food animals. Fewer studies have focused on host reactions, especially in terms of phage-mediated acute immune responses and effects on the gut microbiome.

  • Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

    Abstract Chronic sleep fragmentation (SF) commonly occurs in human populations, and although it does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors ultimately promoting obesity and insulin resistance.

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