Invisible yet crucial, our microbial partners add a gene-swapping plot twist to evolutionary theory.
Long-term antibiotic treatment in mice decreases levels of disease-causing plaques and enhances neuroinflammatory activity of microglial cells.
Studies have shown that bariatric surgery can lead to remission of type 2 diabetes mellitus (T2DM) in rodents and humans, but this beneficial effect cannot be explained solely by weight loss.
The bacteria in your gut do more than break down your food.
A team of scientists from Oxford University has shown how the natural movement of bacteria could be harnessed to assemble and power microscopic ‘windfarms’ — or other human-made micromachines such as smartphone components.
Fighting infection in the gut relies on a dynamic relationship between the cells that line gut walls and microbiota – the hundreds of different bacteria that co-exist within the human body without causing harm.
Abstract The human intestine is a dynamic organ where the complex host-microbe interactions that orchestrate intestinal homeostasis occur.
A team of investigators from Brigham and Women’s Hospital and the University of Massachusetts have developed a suite of computer algorithms that can accurately predict the behavior of the microbiome – the vast collection of microbes living on and inside the human body.
Weill Cornell Medicine researchers will use tools and technologies from Qiagen and CosmosID in a global study that the partners said today will collect DNA and RNA samples from high-traffic areas in subway systems, buses, and parks in 54 cities worldwide, the companies said today.
Bacteria have co-evolved with us for thousands of years. We now understand that they are closely linked to many aspects of health. But, in most cases, the complex influences of microbiota on our health is not yet functionally understood.
There is a report out from the American Academy of Microbiology that is based on the “Microbiology of the Built Environment” colloquium they hosted in September 2015.
What are microbiomes and how many do you have in your body? Read the comic or watch the video here: PHD Comics.
The “microbiome” is a bustling city of diverse and dynamic bacteria, and its potential for helping patients has scientists and researchers excited for the future.
The volume of published studies employing axenic or germ-free mice increased dramatically over the past 15 years, in part due to growing interest in microbiome research.
Let’s start with a definition: what is the microbiome? Simply put, the microbiome is the collection of microbes (mostly bacteria) that live in and on your body.
Many microorganisms are “unculturable,” or at least not able to grow in known media. Now, a new tool enables researchers to predict what nutrients organisms need to thrive in the lab, eliminating most of the guesswork involved in setting up new cultures.
At a workshop held at the National Institutes of Health (NIH) last September on the role of human microbiota in infectious disease, I was disheartened not to hear a single talk on the fungal community—the mycobiome.
Join us for a webinar on August 4, 2016 exploring the complex relationship between diet, exercise and the microbiome.
Join us for a webinar on July 26, 2016 introducing the use of the human Inflammatory Bowel Disease (IBD) in the NOG mouse for better preclinical drug candidate profiling.
Abstract Demands for faster and more accurate methods to analyze microbial communities from natural and clinical samples have been increasing in the medical and healthcare industry.
Abstract Duodenum-jejunum gastric bypass (DJB) has been used to treat morbid diabetic patients. However, neither the suitability among patients nor the mechanisms of this surgical treatment is clear.
Abstract The aim of this work was to investigate the relationship between the structure of gut microbial communities fed with different diets (i.e. high-protein – HP – vs. high-fiber – HF – diet) and their functional stability when challenged with mild and acute doses of a mix of amoxicillin, ciprofloxacin and tetracycline.
Abstract Background Humans are increasingly exposed via the diet to Ag nanoparticles (NP) used in the food industry. Because of their anti-bacterial activity, ingested Ag NP might disturb the gut microbiota that is essential for local and systemic homeostasis.
Abstract Longitudinal studies aim typically at following populations of subjects over time and are important to understand the global evolution of biological processes.
Abstract Objective: The gut microbiome regulates host immune homeostasis. Rheumatoid arthritis (RA) is associated with intestinal dysbiosis. In this study we used a human gut-derived commensal to modulate immune response and treat arthritis in a humanized mouse model.