Q&A: Friends (but sometimes foes) within: the complex evolutionary ecology of symbioses between host and microbes

ABSTRACT Over the past decade, there has been a pronounced shift in the study of host–microbe associations, with recognition that many of these associations are beneficial, and often critical, for a diverse array of hosts. There may also be pronounced benefits for the microbes, though this is less well empirically understood. Significant progress has been […]


The Association for Gnotobiotics, Inc. invites you to join our revitalized organization!!

The Association for Gnotobiotics, Inc. invites you to join our revitalized organization!! Following many years of inactivity, the current AG council has been working tirelessly to reorganize. In the past year we have had the organization’s incorporation status reinstated with the State of Wisconsin where the organization was first incorporated in 1966. We have also […]


Growing Roster of Speakers, Spanning Research and Industry, Announced for 4th Annual Translational Microbiome Conference

Contact: John Waslif, Managing Director, Arrowhead Publishers and Conferences Phone: 866-945-0263 (extension 700) Email: john.waslif@arrowheadpublishers.com Website: arrowheadpublishers.com Conference topics will feature speakers and panels on animal models, bioinformatics challenges, intellectual property management, investment deals and approaches, pharma deals in the microbiome space, and the need for standards. MINNEAPOLIS, November 28, 2017– Arrowhead Publishers unveils a […]


Microbiome Drug Development Event

Despite increased investment, there are still major challenges generating effective pre-clinical data and translating that into the clinic; including building an effective CMC strategy that allows a realistic scale-up. Another major challenge is navigating the regulatory landscape in Europe which is becoming increasingly difficult and has even resulted in companies setting up offices in the […]


Uncovering the function of host-associated microbial communities

This post is by MSU grad student Connie Rojas: Microbes colonize every surface of their hosts. Once established, they do not live in isolated patches, but instead form highly regulated, structurally and functionally organized communities, termed ‘microbiota’.


WEBINAR: How to Harness the Microbiome – Considerations and Implications of the Microbiome in Preclinical Research with Reproducible Results

Taconic On-Demand Webinar As our knowledge of the microbiome grows, its confounding experimental impacts generate concern about reproducibility in animal model research. Are you properly controlling for its effects?


Opinion: Microbiology Needs More Math

By Mikhail Tikhonov: Empirical data and humans’ biased interpretations can only get so far in truly understanding life at the microscale.


Progress Uncovering the Mysteries of the Human Microbiome

This blog is authored by members of the CDD Vault community. CDD Vault is a hosted drug discovery informatics platform that securely manages both private and external biological and chemical data…Nigel R. A. Beeley, Ph.D.:


SCITECH | Exploring alternative causes of Alzheimer’s

Saishree Badrinarayanan: Microbes and infections might cause Alzheimer’s disease What do Herpes simplex virus type 1 (HSV1), Chlamydia and Syphilis have to do with Alzheimer’s disease?


Oklahoma’s first germ-free mouse research facility opens in Oklahoma City

The Oklahoma Medical Research opened its new Gnotobiotic Mouse Core (GMC) Facility Thursday in Oklahoma City.


Microbiome-Centric Human Health: A Call for Systems Biology

The Scientist is bringing together a panel of experts who will share their research, summarize the state of the science, and discuss the next steps in developing personalized microbiome-based therapies.


Protein Links Gut Microbes, Biological Clocks, and Weight Gain

by Dr. Francis Collins: The American epidemic of obesity is a major public health concern, and keeping off the extra pounds is a concern for many of us.


BUGS ON THE BRAIN: THE MICROBIOTA-GUT-BRAIN AXIS

By Eamonn M. M. Quigley, Chief Division of Gastroenterology and Hepatology, Houston Methodist Hospital and Professor of Medicine, Weill Cornell Medical College, Houston, Texas, USA.


The Frenemy Inside You: tales of bacterial cooperation and collusion

MAYA EMMONS-BELL, PhD student in biology: You are roughly half bacteria. In terms of cell number, that is. It’s a disorienting reality to swallow,


New insights regarding how targeting the gut microbiome can improve longevity in the worm Caenorhabditis elegans

Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics: Previous research has shown the aging process and frailty may be associated with a perturbed gut microbiome in elderly people.


Mice eating SH1 get sick

Bart’s MS Blog Berer K, Gerdes LA, Cekanaviciute E, Jia X, Xiao L, Xia Z, Liu C, Klotz L, Stauffer U, Baranzini SE, Kümpfel T, Hohlfeld R, Krishnamoorthy G, Wekerle H.Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. Proc Natl Acad Sci U S A. 2017. pii: 201711233.


Microbiome Connections to Disease Get Stronger

In the pipeline: Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog from the publishers of Science Translational Medicine. A fair amount of what you read about the human microbiome is hype. There’s no way around it.


2017 MICROBIOME IN MOUSE MODELS WORKSHOP REVIEW — BEST PRACTICES

By Philip Dubé, PhD – Part III: Best Practices for Study Design


ARE DIRTY MICE SUPERIOR IMMUNOLOGY MODELS?

In a recent review article, David Masopust and his coauthors from the University of Minnesota Medical School discuss the relevancy of mouse models for use in immunological studies and translatability of immune system studies using SPF mice.


Brain blood vessel lesions tied to intestinal bacteria

From “The ZerrKing:” It Is A Platform To Get Latest News & Latest Technology, Idea And Many More: Pre-clinical study links gut microbes, immune system to a genetic disorder that can cause stroke and seizures






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