MINNEAPOLIS, March 29, 2018– Arrowhead Publishers released a parallel nutrition track agenda for the 4th Annual Translational Microbiome Conference, scheduled April 18-20 in Boston. The conference is designed to bring together scientists at the forefront of microbiome research with pioneering business leaders at companies generating microbiome-based medical solutions. Sponsored by Nestlé Health Science, the nutrition […]
It is heavily debated whether the use of the weedkiller glyphosate in agriculture and gardening can induce dysbiosis of the gut microbiota, negatively affecting human and animal health. Dysbiosis is an imbalance in the microbiome composition associated with conditions such as colitis, metabolic syndrome, allergies, and more. Herbicide and the Microbiome We recently highlighted new […]
ABSTRACT Microbiome science is revealing that the phenotype and health of animals, including humans, depend on the sustained function of their resident microorganisms. In this essay, I argue for thoughtful choice of model systems for human microbiome science. A greater variety of experimental systems, including wider use of invertebrate models, would benefit biomedical research, while […]
While developing a low-cost alternative to traditional gnotobiotic isolators, a team of researchers at Case Western Reserve University (CWRU) were able to characterize cyclical changes in the microbiomes of gnotobiotic mice. Their research has implications for both the design and affordability of gnotobiotic animal model research. High Cost of Gnotobiotic Isolators Isolators are the gold […]
‘The most that can be expected from any model is that it can supply a useful approximation to reality: All models are wrong; some models are useful.’ This aphorism, simply articulated here by prominent British statistician George Box, gets to the crux of the dilemma we face when considering animal models for the study of […]
I am pleased to draw your attention to this, the first ever topical issue of Brief Reviews in The Journal of Immunology. Through seven Brief Reviews, this issue of The JI highlights the pervasive impact of the gut microbiome on immune functions, both in the gut and at distal sites, and features a cover chosen […]
Animal feed retailer Brogaarden recently launched a new prebiotic diet for foals that can reduce the risk of developing conditions such as Equine Metabolic Syndrome and colitis later in life. The diet works by promoting beneficial gut bacteria, such as Akkermansia muciniphila, in turn inducing regulatory immunity in the foals. The diet’s effects were scientifically […]
ABSTRACT Over the past decade, there has been a pronounced shift in the study of host–microbe associations, with recognition that many of these associations are beneficial, and often critical, for a diverse array of hosts. There may also be pronounced benefits for the microbes, though this is less well empirically understood. Significant progress has been […]
The Association for Gnotobiotics, Inc. invites you to join our revitalized organization!! Following many years of inactivity, the current AG council has been working tirelessly to reorganize. In the past year we have had the organization’s incorporation status reinstated with the State of Wisconsin where the organization was first incorporated in 1966. We have also […]
Contact: John Waslif, Managing Director, Arrowhead Publishers and Conferences Phone: 866-945-0263 (extension 700) Email: email@example.com Website: arrowheadpublishers.com Conference topics will feature speakers and panels on animal models, bioinformatics challenges, intellectual property management, investment deals and approaches, pharma deals in the microbiome space, and the need for standards. MINNEAPOLIS, November 28, 2017– Arrowhead Publishers unveils a […]
Despite increased investment, there are still major challenges generating effective pre-clinical data and translating that into the clinic; including building an effective CMC strategy that allows a realistic scale-up. Another major challenge is navigating the regulatory landscape in Europe which is becoming increasingly difficult and has even resulted in companies setting up offices in the […]
This post is by MSU grad student Connie Rojas: Microbes colonize every surface of their hosts. Once established, they do not live in isolated patches, but instead form highly regulated, structurally and functionally organized communities, termed ‘microbiota’.
Taconic On-Demand Webinar As our knowledge of the microbiome grows, its confounding experimental impacts generate concern about reproducibility in animal model research. Are you properly controlling for its effects?
By Mikhail Tikhonov: Empirical data and humans’ biased interpretations can only get so far in truly understanding life at the microscale.
This blog is authored by members of the CDD Vault community. CDD Vault is a hosted drug discovery informatics platform that securely manages both private and external biological and chemical data…Nigel R. A. Beeley, Ph.D.:
Saishree Badrinarayanan: Microbes and infections might cause Alzheimer’s disease What do Herpes simplex virus type 1 (HSV1), Chlamydia and Syphilis have to do with Alzheimer’s disease?
The Oklahoma Medical Research opened its new Gnotobiotic Mouse Core (GMC) Facility Thursday in Oklahoma City.
The Scientist is bringing together a panel of experts who will share their research, summarize the state of the science, and discuss the next steps in developing personalized microbiome-based therapies.
by Dr. Francis Collins: The American epidemic of obesity is a major public health concern, and keeping off the extra pounds is a concern for many of us.
By Eamonn M. M. Quigley, Chief Division of Gastroenterology and Hepatology, Houston Methodist Hospital and Professor of Medicine, Weill Cornell Medical College, Houston, Texas, USA.