Examining the role of the microbiome in the effectiveness of colorectal cancer treatment

UMass Medical School researchers find connection between bacteria and chemotherapy drugs in lab study


Infant mice lack microbes that help fight intestinal infection

A new study in mice suggests that newborns are more susceptible to intestinal infection because they harbor undeveloped gut microbiomes, and also hints at a way to boost colonization of healthy microbes that protect from pathogens.


Inflammation, gut microbiota, and obesity: What’s the link?

Fast food, gut microbes, sweet drinks, desk jobs: over the years, obesity has been blamed on many things.


Bad mix of gut microbes triggers age-associated inflammation

Inflammation increases with age and this leads to ill-health problems. One of the triggers appears to be the balance of microorganisms in the gut. This is based on studies using mice and the findings may well apply to people.


‘Genetic scalpel’ can manipulate the microbiome, Yale study shows

The gut microbiome is crucial to health, encompassing bacterial communities that possess a hundred times more genes than the human genome.


Giardiasis may be a disease of the ecology of the GI tract

Colonization by the human and animal parasite, Giardia, changed the species composition of the mouse microbiome in a way that might be harmful. The research is published in Infection and Immunity, a journal of the American Society for Microbiology.


‘Genetic scalpel’ can manipulate the microbiome, study shows

The gut microbiome is crucial to health, encompassing bacterial communities that possess a hundred times more genes than the human genome.


Virus may lead to celiac disease through disruption of intestinal immune homeostasis

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye.


This lab-made probiotic fights off infections from unfriendly bacteria

As scientists continue their exploration of the thousands of organisms that live inside our body, a new study is showing just how much one “good” bacteria can be exploited to its host’s advantage.


Age-associated Inflammation Drives Macrophage Dysfunction

Gut microbes are one of the culprits behind age-associated inflammation and premature death in mice, a new study has found. Inflammation increases with age and is a strong risk factor for death in the elderly, but the underlying cause has not been clear.


Gut microbes contribute to age-associated inflammation: Mouse study

Inflammation increases with age and is a strong risk factor for death in the elderly, but the underlying cause has not been clear.


Study links gut microbes to age-related inflammation

New research with mice by McMaster University in Canada suggests gut microbes can lead to age-related inflammation and premature death.


Science News Radio Interview: Taking penicillin while pregnant could affect your baby’s brain

A study on mice suggests that taking the common antibiotic penicillin when pregnant could alter the brain chemistry of your offspring.


Autoimmunity Originates in the Gut

The global prevalence of autoimmune conditions such as type-1 diabetes, rheumatoid arthritis, and celiac disease has increased rapidly over the most recent decades.


Getting antibiotics as a baby may have lasting effects on brain, behavior

Mouse study backs up human observations showing long-term changes.


NIH Wants to Test New Bacteria Therapy for Eczema

Wanted: A few adults and a few more kids who don’t mind having some bacteria sprayed on their skin.


Young poo’ makes aged fish live longer

The gut microbes of young killifish can extend the lifespans of older fish – hinting at the microbiome’s role in ageing.


Key Regulator of Intestinal Homeostasis Identified

SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show.


Low-dose penicillin in early life induces long-term changes in behavior

In a landmark study, researchers at St. Joseph’s Healthcare Hamilton and McMaster University have found that providing clinical (low) doses of penicillin to pregnant mice and their offspring results in long-term behavioural changes.


Penn Vet launches new platform to accelerate microbiome research

Studies of the microbiome—the array of bacteria, fungi, viruses, and other microorganisms living in or on a given individual or environment—generate a lot of data.






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