Taconic Biosciences Participates in Second Rodent Research Reference Mission to the International Space Station

Resulting Studies Will Provide Critical Reference Data to Drive Advancements in Human Health Rensselaer, NY — September 3, 2019 – Taconic Biosciences, a global leader in providing genetically engineered animal model solutions, announces its participation in the second Rodent Research Reference (RRR) mission to the International Space Station. Taconic has a history with NASA dating […]


The Microbiomics Standards & Controls Initiative

What is M-SCI? The Microbiomics Standards & Controls Initiative Receive free standards and controls. Improve accuracy and data reproducibility. Help the field of Microbiomics incorporate controls and standards in every experiment. Why Give Away Free Standards & Controls? Availability is Key to Standardization Leaders in the field of microbiomics have recognized that the lack of […]


Antimicrobial resistance and the microbiome

Microbiome, Environmental Microbiome and Animal Microbiome are coming together to launch a special series inviting authors to submit their research pertaining to antimicrobial resistance (AMR) and the microbiome. The emergence and spread of AMR can only be described as a catastrophic problem for human and animal health. It is projected that there would be more […]


IBD Severity and Fungi in Microbiome

The microbiome includes not just bacteria, but also fungi, viruses and parasites. While most of the attention has been on bacterial components of the microbiome, new research links a commensal yeast found on human skin to disease severity in inflammatory bowel disease (IBD). Linking Common Fungi with IBD Severity In a new paper published in […]


Remodeling unhealthful gut microbiomes to fight disease

You are what you eat — right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer. Today, scientists will report the development of molecules that can […]


Nanoparticle relieved symptoms of inflammatory bowel disease in mice

ANN ARBOR—Researchers at the University of Michigan College of Pharmacy have developed a nanoparticle that alters the gut microbiome and alleviates symptoms of inflammatory bowel disease in mice more effectively than common FDA-approved medications. The gut microbiome––the body’s environment of healthy and unhealthy bacteria––is the next frontier for drug development, and an imbalanced gut microbiome […]


FDA Issues Safety Alert on Investigational Use of Fecal Microbiota Transplantation

Fecal microbiota transplantation (FMT) is the transfer of fecal matter from a healthy individual into a recipient with the goal of treating an ailment. In its simplest form FMT has been used to treat disease with reports detailing its use as far back as 1700 years ago in China1. Modern applications of this procedure have […]


New Mouse Model Predicts Two Clinical Trial Failures in Humans

A new mouse model designed with a microbiome similar to that of wild mice may be a better predictor of human responses to some drugs than commonly used lab mice, according to a study published today in Science. The authors repeated two preclinical studies that had demonstrated positive results in mice only to fail when […]


Using a more diverse microbiome, scientists look to create a better lab mouse

Lab mice are notoriously clean: To prevent introducing anything that could disrupt results, researchers house them in sterile conditions, and the food and water they ingest are monitored for extreme quality. This also means that the mice’s microbiomes — the cohort of microorganisms that reside within all animals and influence many body processes — have […]


Microbiomes of Lab Mice Take a Walk on the Wild Side

National Institutes of Health scientists have developed a new mouse model that could help to improve the relevance of these invaluable laboratory test animals to human health and disease, and the development of human therapeutics. The new mice, which the researchers have called “wildlings”, have acquired the microbiomes of wild mice, but retain the genetics […]


Bone and the Microbiome Have a Brittle Relationship

Laura McCabe had been living a dual professional life at Michigan State University for more than a decade, studying bone in her lab while teaching medical students gastrointestinal physiology in the classroom, when she came across a call for proposals from the Crohn’s and Colitis Foundation. Could researchers look into how inflammatory bowel diseases affect […]


World Microbiome Day 2019

World Microbiome Day is on June 27th this year. World Microbiome Day began in 2018 to demonstrate its emergence as a subject with global impact. That impact is being felt across a variety of disciplines including science, medicine, and nutrition. This year’s theme is “Bacterial Resistance to Antibiotics” highlighting the need to better understand microbes. […]


Gut Microbe Takes a Share of Our Brain Meds

Swallowing a drug can tilt the gut-brain axis, alleviating the symptoms of neurodegenerative diseases such as Parkinson’s. Yet the axis can resist tilting as though its orientation were maintained by hidden sources of inertia. Suspected inertial dampeners include gut microbes. Although gut microbes have been thought to metabolize and lessen the efficacy of levodopa, the […]


Language, numeracy and logic in microbiome science

To deliver precision therapeutics, microbiome-based medicine will require precision of language, logic and numerical accuracy. Epidemiological lessons of the past suggest that attempts to link almost everything in modern life with the microbiome as a risk factor for disease, without rapprochement with plausible mechanisms, will generate controversy rather than consensus. Read more at Nature Reviews: […]


USF Health convenes first Microbiome Joint Workshop with University of Florida

The University of South Florida and the University of Florida convened a Microbiome Joint Workshop at USF Health on May 28, with research presentations by basic scientists and clinician scientists from both universities. It was an important first step in working together to unravel how different microorganisms living in our guts, on our skin, and […]


EU biotech firms unite in pushing for ‘harmonised’ microbiome therapeutics regulation

The Intestinal Microbiome-based Medicines European Task Group (IMM-ETG) involves Caelus Health, EnteroBiotix, Ferring Pharmaceuticals and Maat Pharma along with Pharmabiotic Research Institute (PRI). “The IMM-ETG has been established to contribute to a harmonised regulatory framework in Europe for the intestinal microbiome products based on the whole ecosystem,” said Dr. Luc Sterkman, CEO of Caelus Health. […]


Priorities for the next 10 years of human microbiome research

Over the past decade, more than US$1.7 billion has been spent on human microbiome research. Major projects are under way in the United States, the European Union, China, Canada, Ireland, South Korea and Japan. This investment has confirmed the importance of the microbiome to human health and development. It is now known, for instance, that […]


The Human Microbiome Project expands the toolbox for studying host and microbiome interactions

Results from three long-term studies following host and microbiome characteristics during pregnancy and preterm birth, inflammatory bowel disease, and prediabetes have expanded our understanding of how humans and microbes interact and the resulting consequences for our health. The studies were funded as part of a second phase of the National Institutes of Health’s Human Microbiome […]


Transportation Affects Gut Microbiome of Laboratory Mice

Experimental controls are at the center of every quality experiment, and understanding the causes of microbiome variability is key to controlling for microbiome-related effects. Researchers that utilize murine models attempt to control for possible microbiome variability by ordering mice from the same vendor, using littermate controls, and employing co-housing strategies1. Given the ongoing research reproducibility […]


Cell Press: Cell Host & Microbe

The Human Microbiome has been a recent area of intense research, rapid progress, and exciting advances. Cell Host & Microbe has published a diverse array of exciting articles related to The Human Microbiome. In this Collection, we present a selection of recent research and review articles on the topic. Read more at Cell Press: Cell […]






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