Stress could be just as unhealthy as junk food

Brigham Young University: We all know that a poor diet is unhealthy, but a new BYU study finds that stress may just as harmful to our bodies as a really bad diet.


Infection via mosquito bite alters Zika virus replication kinetics in rhesus macaques

Abstract For more than three decades it has been recognized that small amounts of vector saliva can significantly alter the infectivity of vector-borne pathogens and subsequent in vivo dynamics.


Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology

Abstract Mouse models have enabled breakthroughs in our understanding of the immune system, but it has become increasingly popular to emphasize their shortcomings when translating observations to humans.


Microbial Genetic Composition Tunes Host Longevity

Highlights •Systematic analysis of longevity-promoting microbial genetic variations •Colanic acid as a pro-longevity natural compound effective in different species


Learning more about the gut microbiota

The GMFH editing team recommends these book selections on the topic.


Chondroitin sulfate disaccharides modified the structure and function of the murine gut microbiome under healthy and stressed conditions

CS disaccharides may enhance intestinal absorption and promote kidney function.


Effects of iron supplementation on growth, gut microbiota, metabolomics and cognitive development of rat pups

Abstract Background Iron deficiency is common during infancy and therefore iron supplementation is recommended.


VIDEO: BioEssays: Brain carnitine deficiency causes nonsyndromic autism with an extreme male bias

Arthur Beaudet discusses the importance of diet, genes, epigenetics, drugs, microbiome, and minor illnesses (especially gastrointestinal) in the hypothesis.


From complex gut communities to minimal microbiomes via cultivation

Highlights •Microbiome research will benefit from the complementary use of culture and molecular approaches.


Detection of Helicobacter pylori in the Gastric Mucosa by Fluorescence In Vivo Hybridization

Abstract In this chapter, we describe a fluorescence in vivo hybridization (FIVH) protocol, using nucleic acid probes, for the detection of the bacterium Helicobacter pylori in the gastric mucosa of an infected C57BL/6 mouse model.


TOOLS AND TRENDS IN IMMUNO-ONCOLOGY

A periodic list of methods, tools and people driving research and development. Our scientists present 10 tools and strategies helping to advance immuno-oncology


Harnessing the Power of PCR Molecular Fingerprinting Methods and Next Generation Sequencing for Understanding Structure and Function in Microbial Communities

Abstract Polymerase chain reaction (PCR) is central to methods in molecular ecology. Here, we describe PCR-dependent approaches useful for investigating microbial diversity and its function in various natural, human-associated, and built environment ecosystems.


Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration

Significance Food is medicine, and diet impacts the risk for and progression of age-related macular degeneration AMD, but we have few clues as to why. We found that wild-type mice fed a high-glycemic-index diet similar in composition to the Western diet developed a disease state that resembles dry AMD.


SteadyCom: Predicting microbial abundances while ensuring community stability

Abstract Genome-scale metabolic modeling has become widespread for analyzing microbial metabolism. Extending this established paradigm to more complex microbial communities is emerging as a promising way to unravel the interactions and biochemical repertoire of these omnipresent systems.


Optical nanofiber ‘hears’ bacteria swim, cancer cells move

At the macroscopic level that’s familiar to us, birds chirp, whales sing and we talk. But at the microscopic level, our cells pulsate, bacteria swim and pressure waves ripple on a scale we can’t reach.


Dirt Is Good: The Advantage of Germs for Your Child’s Developing Immune System

by Jack Gilbert (Author), Rob Knight (Author) From two of the world’s top scientists


THE REAL IMPACT OF RODENT DIET ON MICROBIOME AND GUT HEALTH RESEARCH WEBINAR Q&A

Dr. Michael Pellizzon of Research Diets, Inc., recently presented a webinar on the underappreciated impact of rodent diets on microbiome and gut health research, where simple husbandry decisions can profoundly affect both animal model phenotypes and experimental outcomes.


Evolving as a holobiont

Some of the most exciting recent advances in biology have been in our understanding of how the microbiome—the community of bacteria, fungi, and other single-celled microorganisms—influences host functions and behaviors.


Modern Tools and Techniques to Understand Microbes

Foreword Microbiology is one of the leading branches of modern biology and is interdisciplinary in scope as it interfaces with various basic and applied disciplines of science,


The Language of Microbial Culture: Explaining Prebiotics, Probiotics, Synbiotics and Postbiotics

It’s no secret that it’s one of my favorite subjects—the burgeoning field of human gastrointestinal microbiology. I know…it’s easy to get caught up in the comparative excitement of it all.






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