Alterations in the gut microbiota can elicit hypertension in rats

Abstract Gut dysbiosis has been linked to cardiovascular diseases including hypertension.


Antibiotic exposure perturbs the gut microbiota and elevates mortality in honeybees

Abstract Gut microbiomes play crucial roles in animal health, and shifts in the gut microbial community structure can have detrimental impacts on hosts.


Fecal microbiota transplantation (FMT) could reverse the severity of experimental necrotizing enterocolitis (NEC) via oxidative stress modulation

Highlights •FMT could eliminate the O2•– production and promote the NO production in the experimental NEC mice though modulation of S-glutathionylation of eNOS. •FMT decreases the extent of TLR4-mediated proinflammatory signaling, though TLR9 in intestinal mucosa tissue.


Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism

Abstract Gut microbiota dysbiosis has been implicated in a variety of systemic disorders, notably metabolic diseases including obesity and impaired liver function, but the underlying mechanisms are uncertain.


The role of adaptive immunity as an ecological filter on the gut microbiota in zebrafish

Abstract All animals live in intimate association with communities of microbes, collectively referred to as their microbiota.


Gut microbes and the developing brain

Abstract The discovery that commensal gut microbiota can influence host development and physiology beyond the gastrointestinal (GI) tract has triggered a paradigm shift in our conceptualization of the origin of human diseases.


Moderate dietary protein restriction alters the composition of gut microbiota and improves ileal barrier function in adult pig model

Abstract This study was conducted to investigate impacts of dietary protein levels on gut bacterial community and gut barrier.


NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth

Abstract Inflammatory bowel diseases involve the dynamic interaction of host genetics, the microbiome and inflammatory responses.


Toxin-positive Clostridium difficile latently infect mouse colonies and protect against highly pathogenic C. difficile

Abstract Objective Clostridium difficile is a toxin-producing bacterium and a leading cause of antibiotic-associated disease.


IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice

Significance Immunoglobulins exist in several forms, or isotypes, that carry out distinct effector functions.


Effect of predatory bacteria on the gut bacterial microbiota in rats

Abstract Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus are Gram-negative proteobacteria that are obligate predators of other Gram-negative bacteria and are considered potential alternatives to antibiotics.


Gut microbiota analysis in rats with methamphetamine-induced conditioned place preference

Abstract Methamphetamine abuse is a major public health crisis. Because accumulating evidence supports the hypothesis that the gut microbiota plays an important role in central nervous system (CNS) function,


A gut reaction: The combined influence of exercise and diet on gastrointestinal microbiota in rats

Abstract AIMS: Intestinal microbiota modulates the development of clinical conditions, including metabolic syndrome and obesity.


Unexplored Archaeal Diversity in the Great Ape Gut Microbiome

ABSTRACT Archaea are habitual residents of the human gut flora but are detected at substantially lower frequencies than bacteria.


Microbiota alteration is associated with the development of stress-induced despair behavior

Abstract Depressive disorders often run in families, which, in addition to the genetic component, may point to the microbiome as a causative agent.


The link between inflammation, bugs, the intestine and the brain in alcohol dependence

Abstract In recent years, some new processes have been proposed to explain how alcohol may influence behavior, psychological symptoms and alcohol seeking in alcohol-dependent subjects.


Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

Connecting the gut-brain axis Irritable bowel syndrome (IBS), the most common gastrointestinal disorder worldwide, is characterized by abdominal pain and altered gut function and often is accompanied by anxiety.


Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

Connecting the gut-brain axis Irritable bowel syndrome (IBS), the most common gastrointestinal disorder worldwide, is characterized by abdominal pain and altered gut function and often is accompanied by anxiety.


GMPR: A novel normalization method for microbiome sequencing data

Abstract Normalization is the first and a critical step in microbiome sequencing (microbiome-Seq) data analysis to account for variable library sizes.


IMPACT OF TIGECYCLINE VERSUS OTHER ANTIBIOTICS ON THE FECAL METABOLOME AND ON COLONIZATION RESISTANCE TO CLOSTRIDIUM DIFFICILE IN MICE

Abstract Background The glycylcycline antibiotic tigecycline may have a relatively low propensity to promote Clostridium difficile infection






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