A single genetic change in gut bacteria alters host metabolism

Posted by: | July 23, 2018 | Comments

A single genetic change in gut bacteria alters host metabolism

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journal eLife.

The research provides an important step towards understanding how the microbiome – the bacteria that live in our body – affects metabolism.

It is well established that the microbiome influences the development of obesity and metabolic diseases such as diabetes. But although these associations are well known, the specific ways in which the microbiome affects metabolism are harder to decipher. This is because the gut contains so many species of bacteria producing many different kinds of metabolites. Untangling their different effects is a significant challenge.

Read more at: eLife






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