Alterations in the microbiome have an acknowledged role in cancer pathology1,2. Earlier this year, however, researchers at New York University published a manuscript3 connecting the pancreatic microbiome to cancer progression.
In this report, Pushalkar et al. demonstrate that the endogenous microbiome of the pancreas can drive immunosuppressive conditions in humans and mice, which creates a pro-tumorigenic state. Treatment regimens that include modulating the microbiome show promise for treating pancreatic cancer.
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