New research with mice by McMaster University in Canada suggests gut microbes can lead to age-related inflammation and premature death.
Researchers found that imbalances in the composition of gut microbes in older mice cause the intestines to become leaky and release bacterial products that trigger inflammation, impair immune function and reduce lifespan.
Inflammation can make older adults more susceptible to infections, chronic conditions like dementia and cardiovascular disease, and early death.
Researchers studied the effects of inflammation by raising mice in germ-free environments and compared them to mice raised in conventional settings. The germ-free mice did not show age-related increases in inflammation and a larger proportion lived longer than mice in the conventional setting.
Find out more at: UPI