Chronic nonbacterial prostate inflammation in a rat model is associated with changes of gut microbiota that can be modified with a galactoglucomannan‐rich hemicellulose extract in diet

Posted by: | October 8, 2018 | Comments

ABSTRACT

Objectives

To investigate dietary effects on the gut microbiota composition in a rat model of chronic non‐bacterial prostate inflammation.

Materials and Methods

Chronic nonbacterial prostate inflammation in the Wistar rat strain was induced with subcutaneous testosterone and 17β‐oestradiol hormone pellets for 18 weeks. Rats with placebo pellets served as healthy controls. Rats with chronic prostate inflammation were stratified into two groups, which drank either plain tap water (control group) or tap water supplied with 2% galactoglucomannan‐rich hemicellulose extract (GGM group) from Norway spruce (Picea abies) for five weeks before sacrifice.

Read more at: Wiley Online Library

Yvonne Konkol, Anniina Keskitalo, Heikki Vuorikoski, Sami Pietilä, Laura L Elo, Eveliina Munukka, Jenni Bernoulli, Johanna Tuomela. BJU International. DOI: https://doi.org/10.1111/bju.14553. 26 September 2018.





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