Lifelong calorie restriction affects indicators of colonic health in aging C57Bl/6J mice
Diminished colonic health is associated with various age-related pathologies. Calorie restriction (CR) is an effective strategy to increase healthy lifespan, although underlying mechanisms are not fully elucidated. Here, we report the effects of lifelong CR on indicators of colonic health in aging C57Bl/6J mice.
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Dieuwertje E.G.Kok, Fenni Rusli, Benthe van der Lugt, Carolien Lute, Luca Laghi, Stefano Salvioli, Gianfranco Picone, Claudio Franceschi, Hauke Smidt, Jacques Vervoort, Ellen Kampman, Michael Müller, and Wilma T.Steegenga. ScienceDirect. DOI: https://doi.org/10.1016/j.jnutbio.2018.01.001
. June 2018