The mammalian mycobiome: A complex system in a dynamic relationship with the host

Posted by: | October 4, 2018 | Comments

ABSTRACT

The mammalian mycobiome: A complex system in a dynamic relationship with the host

Mammalian barrier surfaces are densely populated by symbiont fungi in much the same way the former are colonized by symbiont bacteria. The fungal microbiota, otherwise known as the mycobiota, is increasingly recognized as a critical player in the maintenance of health and homeostasis of the host. Here we discuss the impact of the mycobiota on host physiology and disease, the factors influencing mycobiota composition, and the current technologies used for identifying symbiont fungal species. Understanding the tripartite interactions among the host, mycobiota, and other members of the microbiota, will help to guide the development of novel prevention and therapeutic strategies for a variety of human diseases.

Read more at: Wiley Online Library

Ghee Chuan Lai, Tze Guan Tan, Norman Pavelka. WIREs Systems Biology and Medicine. DOI: https://doi.org/10.1002/wsbm.1438. 25 September 2018.





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