Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation

Posted by: | July 10, 2023 | Comments


Ben Libberton, Postdoc and Public Information Officer, Karolinska Institute…researcher at the Swedish Medical Nanoscience Center in Stockholm.

New research from Elisabeth Grice and Phillip Scott at the University of Pennsylvania has shown that dysbiosis in the skin of lab mice was transimissible and promoted higher levels of skin inflammation.

The team began in vivo experiments after discovering a trend in the microbiome of Leishmania infected individuals in Brazil with the help of their collaborators at Universidade Federal da Bahia. The saw that infected people had dysbiotic microbiomes with reduced diversity which were dominated by staphylococci and streptococci.

This finding was mirrored in a mouse model. What was surprising was that the dysbiotic microbiome could be transferred to uninfected mice sharing the same cage. The uninfected mice then showed increased inflammation and when they were eventually infected with L. major, had much worse symptoms.

Read the rest at: Biofilms and Microbiomes






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