FDA Issues Safety Alert on Investigational Use of Fecal Microbiota Transplantation

Posted by: | August 20, 2019 | Comments

FDA Issues Safety Alert on Investigational Use of Fecal Microbiota Transplantation

Fecal microbiota transplantation (FMT) is the transfer of fecal matter from a healthy individual into a recipient with the goal of treating an ailment. In its simplest form FMT has been used to treat disease with reports detailing its use as far back as 1700 years ago in China1. Modern applications of this procedure have been developed to treat Clostridium difficile infections, colitis, and irritable bowel syndrome with treatment options being explored for numerous other maladies. In preclinical studies, FMT is an important tool in microbiome research that enables researchers the opportunity to study the effects of a given microbiota once transplanted into a germ-free mouse.

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