Rederivation of Mouse Models at Higher Health Statuses

Posted by: | January 29, 2019 | Comments

Rederivation of Mouse Models at Higher Health Statuses

Rederiving murine research models is the process of transferring embryos from one animal into another which is either germ-free or hosts only specifically identified microbiota. This “resets” the health status of the line, allowing the offspring of mice or rats that were previously infected with either viruses, parasites, or bacteria to be used in research studies.

This article will review the process of rederiving a mouse line and which health statuses the offspring can be generated at.

Read more at Taconic Insights.






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