Effects of theabrownin on serum metabolite and gut microbiome in rats with high-sugar diet

Posted by: | September 19, 2019 | Comments

ABSTRACT

Effects of theabrownin on serum metabolite and gut microbiome in rats with high-sugar diet

Evidence has accumulated that the gut microbiota is an important environmental factor contributing to obesity by altering host energy harvest and storage. We performed a high-throughput 16S rDNA sequencing association study and serum metabolomics profiling in rat with high-sugar diet. Our studies revealed that high sugar diet reduced the diversity of cecal microorganisms, while the combination of theabrownin and high sugar diet increased the diversity of cecal microorganisms and promoted reproduction of Alloprevotella, Coprostanoligenes_group, Bacteroides, Prevotellaceae_NK3B31_group, Desulfovibrio, Intestinimonas, Alistipes, Bifidobacterium, Phascolarctobacterium , Ruminococcaceae_UCG-010 and Staphylococcus.

Read more at: RSC Publishing

Suijuan Yue, Dan Zhao, Chun-xiu Peng, Chao Tan, Qiuping Wang and Jia shun Gong. Food & Function. DOI: 10.1039/C9FO01334B. 04 Sep 2019.





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