Intake of Watermelon or Its Byproducts Alters Glucose Metabolism, the Microbiome, and Hepatic Proinflammatory Metabolites in High-Fat–Fed Male C57BL/6 J Mice

Posted by: | November 14, 2019 | Comments

ABSTRACT

BACKGROUND

Intake of Watermelon or Its Byproducts Alters Glucose Metabolism, the Microbiome, and Hepatic Proinflammatory Metabolites in High-Fat–Fed Male C57BL/6 J Mice

Watermelon intake has demonstrated effects on blood pressure regulation along with other health benefits.

OBJECTIVE

We hypothesized that intake of whole watermelon and products made from watermelon rind (WR) and watermelon skin (WS) would remediate metabolic complications in C57BL/6 J male mice fed a diet modeling a Western-style diet.

METHODS

Ten-week-old male C57BL/6 J mice were provided either a low-fat (LF) diet [10% fat (by energy), 8% sucrose (by energy) and no added cholesterol], a high-fat (HF) diet [45% fat (by energy), 20% kcal sucrose (by energy), and 1% (w/w) cholesterol], or an HF diet plus WS, WR, or watermelon flesh (WF) for 10 wk.

Read more at: Oxford Academic

Alexandra R Becraft, Marlena L Sturm, Rufa L Mendez, Si Hong Park, Sang In Lee, Neil F Shay. The Journal of Nutrition. DOI: https://doi.org/10.1093/jn/nxz267. 11 November 2019.





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