Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults

Posted by: | September 25, 2019 | Comments

ABSTRACT

Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults

Evidence in support of a gut-muscle axis has been reported in rodents, but studies in older adult humans are limited. Accordingly, the primary goals of the present study were to compare gut microbiome composition in older adults that differed in terms of the percentage of whole body lean mass and physical functioning (high-functioning, HF, n = 18; low-functioning, LF, n = 11), and to evaluate the causative role of the gut microbiome on these variables by transferring fecal samples from older adults into germ-free mice.

Read more at: Science Direct

Roger A. Fielding, Andrew R. Reeves, Ravi Jasuja, Christine Liu, Brittany B.Barrett, and Michael S.Lustgarten. Science Direct. DOI: https://doi.org/10.1016/j.exger.2019.110722. 04 Sep 2019.





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