Pomegranate peel extract alters the microbiome in mice and dysbiosis caused by Citrobacter rodentium infection

Posted by: | July 12, 2019 | Comments

Alpha‐ and beta‐diversity plots for water‐ or PPX‐treated mice

ABSTRACT

Treatment of mice with a pomegranate peel extract (PPX) decreased the pathogenicity of Citrobacter rodentium (Cr) infections. Here, we investigate the effects of PPX on the microbiome of uninfected or Cr‐infected C3H/HeNCr mice by 16S rRNA gene sequencing. Mice were treated with water or PPX for 14 days, feces were collected, and then, the mice were infected with Cr and feces collected again at day 6 postinfection. DNA was isolated from the fecal samples and subjected to 16S rRNA gene sequencing to determine the microbial composition.

Read more at: Wiley Online Library

Nadja S. George, Lumei Cheung, Devanand L. Luthria, Monica Santin, Harry D. Dawson, Arvind A. Bhagwat, and Allen D. Smith. Food Science & Nutrition. https://doi.org/10.1002/fsn3.1106. 07 July 2019.





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