Strain specific stress-modulating effects of candidate probiotics: a systematic screening in a mouse model of chronic restraint stress

Posted by: | December 2, 2019 | Comments

Background

Strain specific stress-modulating effects of candidate probiotics: a systematic screening in a mouse model of chronic restraint stress

Changes in the gut microbiota have been implicated in mood and cognition. In rodents, supplementation with certain bacteria have been shown to alleviate adverse effects of stress on gut microbiota composition and behaviour, but little is known of how the performance of different strains compare to each other. We took a systematic approach to test the efficacy of twelve candidate probiotic strains from ten species/sub-species of Bifidobacterium and Lactobacillus on behaviours and neuroendocrine responses of chronically stressed mice.

Read more at: ScienceDirect

Lotta K. Stenmana, Elaine Patterson, Johann Meunier, Francois J.Roman, Markus J.Lehtinen. Elsevier. DOI: https://doi.org/10.1016/j.bbr.2019.112376. 22 November 2019.





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