Microbiomics: Zymo Research’s Metagenomics Services Ensure No Microbe is Left Behind
Zymo Research Corporation, The Epigenetics Company, continues to expand its portfolio of products and services for researchers and clinicians alike. Today, the company has announced their new offering of Next-Gen sequencing-based Microbiomics Services that include Taxonomic Profiling and Microbiome Shotgun Sequencing.
Microbial communities thrive in diverse niches under different conditions where they can elicit a strong influence on their environment. This is especially true of the mutualistic relationship between gut flora and humans. Though people can survive without gut flora, the microorganisms perform a host of useful functions, such as fermenting unused energy substrates, training the immune system, preventing growth of harmful, pathogenic bacteria, regulating the development of the gut, producing vitamins for the host, such as biotin and vitamin K, and producing hormones to direct the host to store fats. However, in certain conditions, some species are thought to be capable of causing disease by producing infection or increasing cancer risk for the host.
Researchers studying microbial communities need to know what organisms comprise a specific population. However, there are many challenges to doing so accurately as many microorganisms cannot be cultured in the lab using present technologies. The solution is the Microbiomics Taxonomic Profiling and Microbiome Shotgun Sequencing services from Zymo Research which can accurately determine the identity and abundance of micro-organisms from DNA isolated from feces, soil, saliva, etc. The Taxonomic Profiling Service utilizes sequencing of variable regions within the 16S rRNA genetic locus, and high sensitivity afforded by this Taxonomic Profiling technique allows researchers to identify/characterize rare genera of bacteria and archae. The Microbiome Shotgun Sequencing service allows assembly, clustering, classification, and annotation of genetic information for microbial species identification. Zymo Research’s proprietary bioinformatics pipelines provide researchers with publication-quality data for easy interpretation and representation of their discoveries.
Zymo Research is no newcomer to the field of environmental DNA purification. Their industry leading products feature state-of-the-art isolation and purification technologies for ultra-pure DNA with the complete removal of PCR-inhibitors that may be present in some samples. This ensures unbiased, accurate analysis of all microbes in a sampled community. In addition to their microbiomics service offerings, Zymo Research is a fully established genetics/epigenetics services provider.
Irvine, California (PRWEB) May 22, 2014
Read more at: Zymo Research